BDBM50341914 1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid::BPH-735::CHEMBL1765149
SMILES CCCCCCCCCCCCNCC(P(O)(O)=O)P(O)(O)=O
InChI Key InChIKey=MTPROXDBHCNBRU-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50341914
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 3.70E+5nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 811nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair