BDBM50342750 CHEMBL1771484::N,8-dihydroxy-8-(2-(4-(prop-2-ynyloxy)benzylidene)hydrazinyl)octanamide
SMILES ONC(=O)CCCCCCC(=O)NN=Cc1ccc(OCC#C)cc1
InChI Key InChIKey=YKIVECDGASVMLO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50342750
Affinity DataIC50: 2.10nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute
Curated by ChEMBL
Howard Hughes Medical Institute
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair