BDBM50342799 5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770585

SMILES COc1cc(cc(OC)c1OC)N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O

InChI Key InChIKey=FCQFHRMDZZRIPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50342799   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50342799(5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50342799(5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ovine COX2 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50342799(5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of ovine COX1 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50342799(5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed