BDBM50343050 4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide::CHEMBL1770698

SMILES CN(C)c1ccc(cc1)C(=O)C1CCN(CC1)c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO

InChI Key InChIKey=RCSWIFOOANTXTQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343050   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343050(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343050(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343050(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343050(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed