BDBM50343912 1-(2-(4-(2-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine::CHEMBL1775099
SMILES FC(F)(F)c1ccccc1Oc1ccc(OCCN2CCCC2)cc1
InChI Key InChIKey=MPJYOPKKQPYVHK-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50343912
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of purified COX1 assessed as formation of oxidized TMPD during reduction og PGG2 to PGH2 preincubated for 15 mins by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-induced PGE2 production after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of purified COX2 assessed as formation of oxidized TMPD during reduction og PGG2 to PGH2 preincubated for 15 mins by chromogenic assayMore data for this Ligand-Target Pair