BDBM50344415 CHEMBL1779844::N-Isopropyl-6-phenylethynyl-nicotinamide

SMILES CC(C)NC(=O)c1ccc(nc1)C#Cc1ccccc1

InChI Key InChIKey=VLHBXYLYULVLGT-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344415   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50344415(CHEMBL1779844 | N-Isopropyl-6-phenylethynyl-nicoti...)
Affinity DataKi:  7.10E+3nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50344415(CHEMBL1779844 | N-Isopropyl-6-phenylethynyl-nicoti...)
Affinity DataEC50:  62nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as increase of L-glutamate-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed