BDBM50344753 CHEMBL1779526::N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-2-carbonyl)-amino]-terephthalamic acid methyl ester
SMILES COCCOCCOCCOc1cc2CN(CCc3ccc(NC(=O)c4ccc(C(=O)OC)c(NC(=O)c5ccc6ccccc6n5)c4)cc3)CCc2cc1OC
InChI Key InChIKey=ILJPDTWUECJVGE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50344753
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional De Colombia
Curated by ChEMBL
Universidad Nacional De Colombia
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universidad Nacional De Colombia
Curated by ChEMBL
Universidad Nacional De Colombia
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair