BDBM50345240 5-(4-(4-aminobutylamino)pyrimidin-2-yl)benzofuran-2-carboxylic acid::CHEMBL1782511

SMILES NCCCCNc1ccnc(n1)-c1ccc2oc(cc2c1)C(O)=O

InChI Key InChIKey=PSGCMJOKDUMRJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345240   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345240(5-(4-(4-aminobutylamino)pyrimidin-2-yl)benzofuran-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human Pim2 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 90 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345240(5-(4-(4-aminobutylamino)pyrimidin-2-yl)benzofuran-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed