BDBM50345319 CHEMBL1784205::Ethyl 5-chloro-6-(4-{[(3-methylphenyl)amino]carbonyl}piperazin-1-yl)nicotinate

SMILES CCOC(=O)c1cnc(N2CCN(CC2)C(=O)Nc2cccc(C)c2)c(Cl)c1

InChI Key InChIKey=BJORQEIIUZIBIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345319   

TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50345319(CHEMBL1784205 | Ethyl 5-chloro-6-(4-{[(3-methylphe...)
Affinity DataIC50:  240nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50345319(CHEMBL1784205 | Ethyl 5-chloro-6-(4-{[(3-methylphe...)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed