BDBM50345434 5-Ethyl-N-(4-trifluoromethyl)phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::CHEMBL1784711

SMILES CCc1cc(Nc2ccc(cc2)C(F)(F)F)n2ncnc2n1

InChI Key InChIKey=IIJYAMLJLFFDGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345434   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345434(5-Ethyl-N-(4-trifluoromethyl)phenyl-[1,2,4]triazol...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His6-tagged recombinant human dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345434(5-Ethyl-N-(4-trifluoromethyl)phenyl-[1,2,4]triazol...)
Affinity DataIC50:  780nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed