BDBM50345449 8-Oxo-3-(2-(pyrazin-2-yl)ethylthio)-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile::CHEMBL1782083

SMILES O=c1nc2c3cccc4c(SCCc5cnccn5)ccc(c2c1C#N)c34

InChI Key InChIKey=HQIOKZBKQHBBHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345449   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50345449(8-Oxo-3-(2-(pyrazin-2-yl)ethylthio)-8H-acenaphtho[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed