BDBM50345740 3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1785021::CHEMBL2070048::US10544104, Compound 7r::US11247972, Compound 7r::US9765037, Compound 7r

SMILES CCOc1ccc2cc(ccc2c1)-c1nn(C(C)C)c2ncnc(N)c12

InChI Key InChIKey=MJOCJDMQRCJQJF-UHFFFAOYSA-N

Data  2 KI  25 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345740   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataKi:  200nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed