BDBM50345954 3-(4-Bromo-phenyl)-9-(methyl-prop-2-ynyl-amino)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::CHEMBL1784053

SMILES CN(CC#C)c1ccnc2sc3c(ncn(-c4ccc(Br)cc4)c3=O)c12

InChI Key InChIKey=HCWWENOJPGWWSX-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345954   

TargetMetabotropic glutamate receptor 1(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345954(3-(4-Bromo-phenyl)-9-(methyl-prop-2-ynyl-amino)-3H...)
Affinity DataKi:  8nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345954(3-(4-Bromo-phenyl)-9-(methyl-prop-2-ynyl-amino)-3H...)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345954(3-(4-Bromo-phenyl)-9-(methyl-prop-2-ynyl-amino)-3H...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed