BDBM50346026 (R)-2-(3-chloro-4-(methylsulfonyl)phenyl)-3-((R)-3-oxocyclopentyl)-N-(pyrazin-2-yl)propanamide::CHEMBL1783734
SMILES CS(=O)(=O)c1ccc(cc1Cl)[C@@H](C[C@H]1CCC(=O)C1)C(=O)Nc1cnccn1
InChI Key InChIKey=XEANIURBPHCHMG-SWLSCSKDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50346026
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 6.32E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 830nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.42E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair