BDBM50346033 6-(4-Cyano-3-{(R)-3-[2-(3-fluoro-4-methyl-phenyl)-1,1-dimethyl-ethylamino]-2-hydroxy-propoxy}-phenyl)-tricyclo[3.2.1.0*2,4*]octane-3-carboxylic acid::CHEMBL1783931

SMILES Cc1ccc(CC(C)(C)NC[C@@H](O)COc2cc(ccc2C#N)C2CC3CC2C2C3C2C(O)=O)cc1F

InChI Key InChIKey=WGGASNOPFWFLQW-IYBOAGAWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346033   

TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346033(6-(4-Cyano-3-{(R)-3-[2-(3-fluoro-4-methyl-phenyl)-...)
Affinity DataIC50:  23nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed