BDBM50346295 CHEMBL1782375::cis-((1S,3R)-3-(hexahydropyrano[4,3-b]pyrrol-1(6H)-yl)-1-isopropylcyclopentyl)(4-(4-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)methanone
SMILES CC(C)[C@@]1(CC[C@H](C1)N1CCC2COCCC12)C(=O)N1CCN(CC1)c1cc(ccn1)C(F)(F)F
InChI Key InChIKey=PHDISVGKDQNAFO-UXUZRQAQSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50346295
Affinity DataIC50: 23.8nMAssay Description:Antagonist activity at human CCR2 by whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23.8nMAssay Description:Antagonist activity at human CCR2 by whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of labeled dofetilide from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of labeled dofetilide from human ERGMore data for this Ligand-Target Pair