BDBM50346297 CHEMBL1782379::cis-((1S,3R)-3-(3-oxabicyclo[3.3.1]nonan-9-ylamino)-1-isopropylcyclopentyl)(4-(5-(trifluoromethyl)pyridazin-3-yl)piperazin-1-yl)methanone

SMILES CC(C)[C@@]1(CC[C@H](C1)NC1C2CCCC1COC2)C(=O)N1CCN(CC1)c1cc(cnn1)C(F)(F)F

InChI Key InChIKey=CPYOSEQZRMESCN-LXUBISQBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50346297   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346297(CHEMBL1782379 | cis-((1S,3R)-3-(3-oxabicyclo[3.3.1...)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at human CCR2 by whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346297(CHEMBL1782379 | cis-((1S,3R)-3-(3-oxabicyclo[3.3.1...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346297(CHEMBL1782379 | cis-((1S,3R)-3-(3-oxabicyclo[3.3.1...)
Affinity DataIC50:  41nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed