BDBM50346312 CHEMBL1782575::cis-((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydro-2H-pyran-4-ylamino)cyclopentyl)(4-(3-(trifluoromethyl)-1,2,4-thiadiazol-5-yl)piperazin-1-yl)methanone

SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCN(CC1)c1nc(ns1)C(F)(F)F

InChI Key InChIKey=GBWPQTQWSOSZFX-WOYCLPQFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346312   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346312(CHEMBL1782575 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  68.6nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed