BDBM50348708 CHEMBL1801440
SMILES Cc1ccc(cc1)S(=O)(=O)Oc1cc(OCc2ccc(cc2)C(F)(F)F)c(C=C2SC(O)=NC2=O)cc1Br
InChI Key InChIKey=VZLAPPLGBUXEDV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50348708
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of TC-PTP assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of catalytic domain of SHP-1 expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of yeast PTP1 expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataEC50: 340nMAssay Description:Agonist activity at PPARgamma expressed in HepG2 cells co-expressing PPRE assessed as transcriptional activation after 24 hrs by luciferase reporter ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of membrane proximal catalytic domain of LAR-D1 assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair