BDBM50348708 CHEMBL1801440

SMILES Cc1ccc(cc1)S(=O)(=O)Oc1cc(OCc2ccc(cc2)C(F)(F)F)c(C=C2SC(O)=NC2=O)cc1Br

InChI Key InChIKey=VZLAPPLGBUXEDV-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50348708   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of TC-PTP assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of catalytic domain of SHP-1 expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase 1(Saccharomyces cerevisiae)
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of yeast PTP1 expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataEC50:  340nMAssay Description:Agonist activity at PPARgamma expressed in HepG2 cells co-expressing PPRE assessed as transcriptional activation after 24 hrs by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of membrane proximal catalytic domain of LAR-D1 assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed