BDBM5035 CHEMBL235747::N-(5-tert-Butyl-3,4-dimethyl-1,3-thiazol-2(3H)-ylidene)benzenesulfonamide::N-[(2Z)-5-tert-butyl-3,4-dimethyl-2,3-dihydro-1,3-thiazol-2-ylidene]benzenesulfonamide::thiazolidenebenzenesulfonamide deriv. 10r

SMILES Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C

InChI Key InChIKey=XYRMLZVYRVONRR-PEZBUJJGSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 5035   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5035(CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...)
Affinity DataIC50:  4.90E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5035(CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...)
Affinity DataIC50: >5.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM5035(CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...)
Affinity DataIC50:  340nMAssay Description:Displacement of [3H] CP-55,940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM5035(CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgamaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM5035(CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...)
Affinity DataIC50: >5.00E+4nMAssay Description:Displacement of [3H] CP-55,940 from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5035(CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...)
Affinity DataIC50:  5.10E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed