BDBM50351761 CHEMBL1823501
SMILES CCCCCC(=O)NCC#Cc1cn([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)c(=O)[nH]c1=O
InChI Key InChIKey=GXNVKWFHCDPRKH-SQWLQELKSA-L
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50351761
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 8.61E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair