BDBM50352090 CHEMBL1824241

SMILES C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCOCC1)CN1CCCCC1

InChI Key InChIKey=NFMCJKWXWBIFGH-AFARHQOCSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50352090   

TargetHistamine H3 receptor(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataKi:  0.410nMAssay Description:Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]Iodoproxyfan from mouse brain cortex histamine H3 receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataIC50:  6.62E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50352090(CHEMBL1824241)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed