BDBM50353343 CHEMBL1831067

SMILES Cc1cccc(c1)-c1n-2c(C(Oc3ccccc-23)c2ccc(Cl)o2)c2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=WBHDWTSWZKHGQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353343   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50353343(CHEMBL1831067)
Affinity DataIC50:  370nMAssay Description:Inhibition of human wild-type CFTR expressed in FRT cells coexpressing YFP-H148Q assessed as inhibition of cAMP agonist-induced iodide influx after 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed