BDBM50357362 CHEMBL1917103

SMILES [O-][N+](=O)c1ccc2c(c1)S(=O)(=O)N=S2c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=CQXXTFQXVYVGGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357362   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357362(CHEMBL1917103)
Affinity DataIC50:  3.09E+3nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357362(CHEMBL1917103)
Affinity DataIC50:  2.99E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed