BDBM50358742 CHEMBL1922269

SMILES C[C@@H]1[C@H]2CN(CCC3CCOCC3)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F

InChI Key InChIKey=ZJWXPPLSZFSNGB-WRWLIDTKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358742   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50358742(CHEMBL1922269)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50358742(CHEMBL1922269)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human MCHR1 expressed in Jurkat cells co-expressing apoaequorin assessed as inhibition of MCH-induced calcium mobilization by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed