BDBM50358848 CHEMBL1923433

SMILES Cc1[nH]c(C(=O)NC2CCN(CC2)c2ncc(s2)C(O)=O)c(Cl)c1Cl

InChI Key InChIKey=DCKPCHMCUFLQER-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50358848   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358848(CHEMBL1923433)
Affinity DataIC50:  62nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToxin ParE(Escherichia coli)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358848(CHEMBL1923433)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of ATPase activity of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358848(CHEMBL1923433)
Affinity DataEC50:  1.45E+5nMAssay Description:Stimulation of ATPase activity of human MRP2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358848(CHEMBL1923433)
Affinity DataIC50:  20nMAssay Description:Inhibition of ATPase activity of recombinant Staphylococcus aureus DNA gyrase B hybrid tetramer enzyme reconstituted from Escherichia coli GyrA by am...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358848(CHEMBL1923433)
Affinity DataEC50:  2.70E+4nMAssay Description:Stimulation of ATPase activity of rat Mrp2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358848(CHEMBL1923433)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ATPase activity of rat Mrp2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358848(CHEMBL1923433)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ATPase activity of human MRP2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed