BDBM50359524 CHEMBL1927145

SMILES CC(C)(C)OC(=O)N1CCCn2c(C1)c1c(cc2=O)[nH]n(-c2ccccc2Cl)c1=O

InChI Key InChIKey=QAGPTTNFAWOFFR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359524   

TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359524(CHEMBL1927145)
Affinity DataKi:  103nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359524(CHEMBL1927145)
Affinity DataKi:  148nMAssay Description:Antagonist activity at human NOX1 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 5(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359524(CHEMBL1927145)
Affinity DataKi:  590nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359524(CHEMBL1927145)
Affinity DataKi:  1.28E+3nMAssay Description:Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed