BDBM50360467 CHEMBL1934633

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1\C=C\c1ccc(CNC2CC2)cc1

InChI Key InChIKey=OTAJLAURFDNMKV-UKTHLTGXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50360467   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360467(CHEMBL1934633)
Affinity DataIC50:  86nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360467(CHEMBL1934633)
Affinity DataIC50:  98nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed