BDBM50361181 CHEMBL4165344

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCC(CC2)C(=O)NCc2ccc(cc2)C(=O)NO)n1

InChI Key InChIKey=LRLGKFPDGBTGTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361181   

TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50361181(CHEMBL4165344)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of full length human recombinant HDAC1 expressed in baculovirus expression system using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50361181(CHEMBL4165344)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed