BDBM50361216 CHEMBL1934345

SMILES COc1cccnc1-c1ccc2cnc(Nc3ccc(cc3)C3CCN(CC(N)=O)CC3)nn12

InChI Key InChIKey=SYEQKNIMSSBEHO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50361216   

TargetFocal adhesion kinase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361216(CHEMBL1934345)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human 293GT cells after 1 hr by luminescence-based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361216(CHEMBL1934345)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361216(CHEMBL1934345)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of human recombinant FAK expressed in baculovirus expression system after 30 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361216(CHEMBL1934345)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed