BDBM50361444 CHEMBL1938433

SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1

InChI Key InChIKey=PTSASYUIHCGRFT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50361444   

TargetHistone deacetylase 1(Homo sapiens (Human))
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50:  93.8nMAssay Description:Inhibition of HDAC1 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of HDAC3 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50:  65nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50:  25.7nMAssay Description:Inhibition of HDAC6 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of HDAC8 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50:  127nMAssay Description:Inhibition of HDAC4 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed