BDBM50363773 CHEMBL1945137::US9365508, 331a (4-isopropyl)
SMILES CC(C)c1ccc(cc1)C(=O)NC(=S)Nc1ccc(NC(=O)CCCCN(C)C)cc1
InChI Key InChIKey=UTQHGPPEEJLEOE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50363773
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Court of The University of St Andrews
US Patent
University Court of The University of St Andrews
US Patent
Affinity DataIC50: 6.48E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of St. Andrews
Curated by ChEMBL
University Of St. Andrews
Curated by ChEMBL
Affinity DataIC50: 5.71E+3nMAssay Description:Inhibition of recombinant human SitT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Court of The University of St Andrews
US Patent
University Court of The University of St Andrews
US Patent
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of recombinant human SitT1 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of St. Andrews
Curated by ChEMBL
University Of St. Andrews
Curated by ChEMBL
Affinity DataIC50: 3.25E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair