BDBM50363783 CHEMBL1945265::US9365508, 361a (3-Br, 4 tBu)
SMILES CN(C)CCCCC(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(c(Br)c2)C(C)(C)C)cc1
InChI Key InChIKey=ZOGKILKEYWBJEA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50363783
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Court of The University of St Andrews
US Patent
University Court of The University of St Andrews
US Patent
Affinity DataIC50: 1.83E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of St. Andrews
Curated by ChEMBL
University Of St. Andrews
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant human SitT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Court of The University of St Andrews
US Patent
University Court of The University of St Andrews
US Patent
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human SitT1 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of St. Andrews
Curated by ChEMBL
University Of St. Andrews
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair