BDBM50378960 CHEMBL2011242::US9394290, 5

SMILES Brc1ncccc1Cn1ccnc1

InChI Key InChIKey=YTKQMHFKNFYQRF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378960   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50378960(CHEMBL2011242 | US9394290, 5)
Affinity DataIC50:  61nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50378960(CHEMBL2011242 | US9394290, 5)
Affinity DataIC50:  911nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed