BDBM50379138 CHEMBL2012951
SMILES Cc1nc2c(OC(F)F)cccc2n1-c1ccc(s1)C(=O)NC1CC1
InChI Key InChIKey=VQQZSOVXMSWVFT-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50379138
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 using phenacetin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 using diclofenac as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by whole cell voltage clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 using midazolam as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 using S-mephenytoin as substrate after 45 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair