BDBM50379292 CHEMBL2011646
SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(OC(=O)c3c(C)cc(O)cc3O)[C@@H](O)[C@@H]2CO1
InChI Key InChIKey=JCQWLKQBYHSHOG-DAYKGMGPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50379292
Affinity DataKi: 9.85E+3nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
Affinity DataKi: 1.81E+4nMAssay Description:Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using ploy(dA)/oligo(dT)18 as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)1...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DNA polymerase lambda expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of C-terminal-His6-tagged human pol nu expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(d...More data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po...More data for this Ligand-Target Pair
TargetDNA-directed DNA polymerase(Enterobacteria phage T4)
Science University Of Tokyo
Curated by ChEMBL
Science University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of T4 bacteriophage DNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of T4 arnN8l pseT 1 polynucleotide kinase assessed as inhibition of Salmon sperm DNA phosphorylation using [gamma32P]ATP by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agorose gel electrophoresisMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Mus musculus)
Science University Of Tokyo
Curated by ChEMBL
Science University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of mouse IMP dehydrogenase 2More data for this Ligand-Target Pair
TargetDNA polymerase delta catalytic subunit(Homo sapiens (Human))
Science University Of Tokyo
Curated by ChEMBL
Science University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 5.45E+4nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
TargetDNA-directed DNA/RNA polymerase mu(Homo sapiens (Human))
Science University Of Tokyo
Curated by ChEMBL
Science University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human His-tagged recombinant DNA polymerase mu expressed in Escherichia coli BL21 assessed as inhibition of incorporation of dTTP into ...More data for this Ligand-Target Pair