BDBM50379862 CHEMBL2011870
SMILES COc1ccc(cc1)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C
InChI Key InChIKey=HSEURPKENJFQMI-NOZJJQNGSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50379862
Affinity DataIC50: 158nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Negative allosteric modulation of human recombinant mGlu1 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair