BDBM50381224 CHEMBL2018554

SMILES Oc1ccc(\C=C\C=C\C(=O)N2CCCCC2)cc1O

InChI Key InChIKey=ZSGNXVFMAMFAQY-YPCIICBESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381224   

TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  800nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed