BDBM50381284 CHEMBL2018876

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(cc1-[#8])-c1cc2ccc(-[#8])cc2o1

InChI Key InChIKey=ZTGHWUWBQNCCOH-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50381284   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human PDE5A1 catalytic domain (535 to 860) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of human aromatase in term placenta microsome assessed as radioactivityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  8.38E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate assessed as formation of p-nitrophenol preincubated for 15 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  8.38E+4nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition at 10 uMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of human PDE4B2 catalytic domain and UCR2 (92 to 521) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of recombinant PTP1B catalytic domain (unknown origin) assessed as reduction in pNP formation using pNPP as substrate by absorbance based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2 catalytic domain (181 to 506) expressed in Escherichia coli BL21 using [3H]-cAMP/[3H]-cGMP after 15 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed