BDBM50383641 CHEMBL2029845

SMILES CCCOc1ccc(\C=C2/SC(=NC2=O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=QXPQNMORXNOKSB-ATVHPVEESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383641   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383641(CHEMBL2029845)
Affinity DataIC50:  80nMAssay Description:Inhibition of 5-lipooxygenase in cell free S100 freshly isolated human PMNL cells assessed as inhibition of A23187-stimulated 5-LO product formation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383641(CHEMBL2029845)
Affinity DataIC50:  180nMAssay Description:Inhibition of 5-lipooxygenase in human polynuclear leukocytes assessed as inhibition of A23187-stimulated 5-LO product formation preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed