BDBM50386592 CHEMBL2048251
SMILES Clc1cncc(Cl)c1NNC(=O)CCc1ccccc1
InChI Key InChIKey=SPGTWQAWMJWXDP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50386592
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced ethidium bromide uptake after 2 hrs by f...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced IL8 release pretreated for 30 mins before bzAT...More data for this Ligand-Target Pair