BDBM50388707 CHEMBL2059864

SMILES Cc1c[nH]c(n1)-c1ccc(C)c(NC(=O)c2ccc(OCc3ccccn3)cc2)c1

InChI Key InChIKey=GMVNSGUKXHWVSS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388707   

TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388707(CHEMBL2059864)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388707(CHEMBL2059864)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388707(CHEMBL2059864)
Affinity DataEC50:  15nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed