BDBM50389023 CHEMBL2064166::US9353075, 6

SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1

InChI Key InChIKey=PTVDTLVLQXSSEC-GXTWGEPZSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389023   

TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University of California

US Patent
LigandPNGBDBM50389023(CHEMBL2064166 | US9353075, 6)
Affinity DataIC50:  50nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California

US Patent
LigandPNGBDBM50389023(CHEMBL2064166 | US9353075, 6)
Affinity DataIC50:  7nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California

US Patent
LigandPNGBDBM50389023(CHEMBL2064166 | US9353075, 6)
Affinity DataIC50:  14nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
In DepthDetails US Patent