BDBM50389083 CHEMBL2064535
SMILES Fc1ccc(-c2ccc(CSc3nnc(o3)-c3ccc4OCCOc4c3)cc2)c(c1)C#N
InChI Key InChIKey=WYYSOGMUPDEQEM-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50389083
TargetProtein kinase C alpha type(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PKCalpha by FRET assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CDK5/p35 by FRET assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant GSK-3 beta using Ulight-CFFKNIVTPRTPPPSQGK-amide substrate incubated for 90 mins by LANCE method relative to controlMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant GSK-3 alpha using Ulight-CFFKNIVTPRTPPPSQGK-amide substrate incubated for 60 mins by LANCE method relative to controlMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human GSK3BMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CK1epsilon by FRET assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human GSK3AMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant AurKA by FRET assayMore data for this Ligand-Target Pair