BDBM50391955 CHEMBL2152264

SMILES Nc1cccc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1

InChI Key InChIKey=MJYJMOYFDMVCLO-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391955   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50391955(CHEMBL2152264)
Affinity DataKd:  16nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50391955(CHEMBL2152264)
Affinity DataIC50:  42.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50391955(CHEMBL2152264)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed