BDBM50393756 CHEMBL2159198
SMILES Cc1nc2cnc3[nH]ccc3c2n1C1CCCCC1
InChI Key InChIKey=XXXPSYBQNILIFB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50393756
Affinity DataEC50: 100nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-induced STAT3 phosphorylation incubated for 20 mins prior to IL6-induction measur...More data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Inhibition of JAK2 in human TF1 cells assessed as inhibition of EPO-induced STAT5 phosphorylation incubated for 20 mins followed by IL6 challenge for...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-induced STAT3 phosphorylation incubated for 20 mins followed by IL6 challenge for...More data for this Ligand-Target Pair
Affinity DataEC50: 6.60E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Inhibition of JAK2 in human TF1 cells assessed as inhibition of EPO-induced STAT5 phosphorylation incubated for 20 mins prior to EPO-induction measur...More data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair