BDBM50396296 CHEMBL2172477

SMILES CC(=O)Nc1cc(nc(C)n1)-c1c(Nc2ccn(C)n2)nc2ccc(cn12)-c1cccnc1C

InChI Key InChIKey=YQTDIAJNWCPLOM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396296   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50396296(CHEMBL2172477)Copy SMILESCopy InChI

Affinity DataIC50:  15nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50396296(CHEMBL2172477)Copy SMILESCopy InChI

Affinity DataIC50:  4.29E+3nMAssay Description:Inhibition of PI3Kalpha by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI