BDBM50396316 CHEMBL2172635

SMILES COc1cnnc(Nc2cc(nc(C)n2)-c2c(Nc3ccn[nH]3)nc3cccnn23)c1

InChI Key InChIKey=UNITWMRQPUTNPC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396316   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50396316(CHEMBL2172635)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50396316(CHEMBL2172635)Copy SMILESCopy InChI

Affinity DataIC50:  54nMAssay Description:Inhibition of PI3Kalpha by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI