BDBM50400049 CHEMBL2177758::US11191732, Example 2

SMILES Nc1nnc(CCSCCc2nnc(N)s2)s1

InChI Key InChIKey=AOAQKDDVWLOZFV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400049   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM50400049(CHEMBL2177758 | US11191732, Example 2)
Affinity DataIC50:  1.00E+5nMAssay Description:A high throughput screening (HTS) assay and together with NCATS screened over 350,000 compounds in attempt to identify novel GLS inhibitor structures...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM50400049(CHEMBL2177758 | US11191732, Example 2)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair