BDBM50400050 CHEMBL2177757::US10793535, Cmpd ID 1::US11191732, Example BPTES::US8604016, 1::US9938267, Cmpd ID 1

SMILES O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3)s2)s1

InChI Key InChIKey=MDJIPXYRSZHCFS-UHFFFAOYSA-N

Data  29 IC50  2 Kd

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400050   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)
Affinity DataKd:  200nMAssay Description:Binding affinity to recombinant human C-terminal His-tagged GLS1 after 3 hrs in presence of glycine by GDH coupled assayMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS by SPR assayMore data for this Ligand-Target Pair